Yimin Sun, Ph.D.

Part-time Principal Investigator, Shenzhen Institute of Neuroscience
Associate Professor, Tsinghua University Medical School and shenzhen Post-graduate College of Tsinghua University

Dr. Yimin Sun received his PhD from Tsinghua University Medical School, and is the Principal Investigator of SION. He is also the Executive Vice President and Chief Scientific Officer of CapitalBio eHealth Science and Technology Co., Ltd. and holds Associate Professorship at Tsinghua University Medical School and Shenzhen Post-graduate College of Tsinghua University. He is the Executive Council Member of China International Exchange and Promotional Association for Medical and Health Care, Fellow of the Biochip Branch of China Medicinal Biotechnology Association, Fellow of the Precision Medicine of China Medicinal Biotechnology Association, and Fellow of Clinical Trial and Big Data Quality Management Branch of China Quality Association for Pharmaceuticals. Dr. Sun has published over 30 SCI papers, of which 16 as the first or corresponding author, and has been granted 7 invention patents. He led and completed 1 Major Technology Project of Ministry of Health, 1 sub-study of the National Key Science and Technology Project, 1 sub-study of “863”Key Project of Ministry of Science and Technology, 1 project supported by the Young Scientists Fund of the National Natural Science Foundation of China, and is currently leading a “973” National Key Project. The project which he participated, “the Research, Development and Application of Systematic Biochips and Associated Instruments”, was awarded as the “Scientific and Technological Achievement” by Ministry of Education in 2006, and received Runner-up of “Beijing Science and Technology Award” and Runner-up of the “National Technology Invention Award” in 2007.

Selected Publications:

  1. Xu M, Lv X, Xie L, Huang X, Huang Y, Chen Y, Peng K, Wang P, Wang W, Qi L, Bi Y, Sun Y, Ning G. Discrete associations of the GCKR variant with metabolic risk in a Chinese population: longitudinal change analysis. Diabetologia, 2016, 59(2):307-15.
  2. Jiang K, Sun Y, Wang C, Ji J, Li Y, et al. Genome-wide association study identifies two new susceptibility loci for colorectal cancer at 5q23.3 and 17q12 in Han Chinese. Oncotarget, 2015, 6(37):40327-36.
  3. Lu S, Jiao H, Xu J, Zheng Y, Sun Y, Chen H. Downregulation of IL6 Targeted MiR-376b May Contribute to a Positive IL6 Feedback Loop During Early Liver Regeneration in Mice. Cell Physiol Biochem., 2015, 37(1):233-42.
  4. Sun YM, Huang YQ, Yin AH, Pan YC, et al. Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate . Nature Communications, 2015, 6:6414
  5. Chen H, Xu J, Zhou Y, Gao Y, Wang G, Xia J, Huen M, Siok W, Jiang Y, Tan L, Sun Y. Association study of stuttering candidate genes GNPTAB, GNPTG and NAGPA with dyslexia in Chinese population. BMC Genet., 2015, 16(1):7.
  6. Guoqing Wang, Yuxi Zhou, Yong Gao, Huan Chen, Jiguang Xia, Junquan Xu, Michael S.Y. Huen, Wai Ting Siok, Yuyang Jiang, Li Hai Tan, Yimin Sun. Association of specific language impairment candidate genes CMIP and ATP2C2 with developmental dyslexia in Chinese population. Journal of Neurolinguistics, 2015, 33:163-171.
  7. Chen H, Lu S, Zhou J, Bai Z, Fu H, Xu X, Yang S, Jiao B, Sun Y. An integrated approach for the identification of USF1-centered transcriptional regulatory networks during liver regeneration. Biochim Biophys Acta., 2014, 1839(5):415-23.
  8. Sun Y, Gao Y, Zhou Y, Chen H, Wang G, Xu J, Xia J, Huen MS, Siok WT, Jiang Y, Tan LH. Association study of developmental dyslexia candidate genes DCDC2 and KIAA0319 in Chinese population. Am J Med Genet B Neuropsychiatr Genet., 2014, 165B(8):627-34.
  9. Chen H, Wang G, Xia J, Zhou Y, Gao Y, Xu J, Huen MS, Siok WT, Jiang Y, Tan LH, Sun Y. Stuttering candidate genes DRD2 but not SLC6A3 is associated with developmental dyslexia in Chinese population. Behav Brain Funct., 2014, 10(1):29.
  10. Zeng L, Sun Y, Xie L, Wei L, Ren Y, Zhao J, Qin W, Mitchelson K, Cheng J. Construction of a novel oligonucleotide array-based transcription factor interaction assay platform and its uses for profiling STAT1 cofactors in mouse fibroblast cells. Proteomics, 2013, 13(16):2377-85.
  11. Li T, Wang H, Sun Y, Zhao L, Gang Y, Guo X, Huang R, Yang Z, Pan Y, Wu K, Xu L, Liu Z, Fan D. Transcription factor CUTL1 is a negative regulator of drug resistance in gastric cancer. J Biol Chem., 2013, 288(6):4135-47.
  12. Zhang GJ, Li WJ, Li ZQ, Lv H, Ren YH, Ma RM, Li XH, Kang XX, Shi YY and Sun YM. Association between Paraoxonase gene (PON) and stroke in the Han Chinese Population. BMC Medical Genetics, 2013, 14:16.
  13. Guo Y, Liu H, Yang Z, Chen J, Sun Y and Ren X. Identification and characterization of miRNAome in tobacco (Nicotiana tabacum) by deep sequencing combined with microarray. Gene, 2012, 501 (1):24-32.
  14. Sun YM, Zhang Y, Zeng LQ, Wu JP, Ren AH, Wei L, Shao W, Zhao YC, Qiao JY, Zhang L, Mitchelson K and Cheng J. Broad profiling of DNA-binding transcription factor activities improves regulatory network construction in adult mouse tissues. J Proteome Res, 2008, 7(10): 4455-4464.
  15. Zhao M, Sun YM, Gao F, Wu XY, Tang JL, Yin H, Luo YQ, Bruce Richardson, and Lu QJ. RFX1 downregulation causes CD11a and CD70 overexpression in lupus CD4+ T cells. J Autoimmun, 2010, 35(1):58-69.
  16. Chen H, Sun Y, Dong R, Yang S, Pan C, Xiang D, Miao M, Jiao B. Mir-34a Is Upregulated during Liver Regeneration in Rats and Is Associated with the Suppression of Hepatocyte Proliferation. PLoS One, 2011;6(5):e20238