陈欢

副研究员

陈欢，国家蛋白质科学中心·北京（凤凰中心）副研究员。2012年获得第二军医大学博士学位。主要研究方向为蛋白质研究以及中国语言障碍的基因基础。

代表性论文：

  1. Lu S, Jiao H, Xu J, Zheng Y, Sun Y*, Chen H* (corresponding authors). Downregulation of IL6 Targeted MiR-376b May Contribute to a Positive IL6 Feedback Loop During Early Liver Regeneration in Mice. Cell Physiol Biochem, 2015; 37(1):233-242.
  2. Jiao H, Zhu Y, Lu S, Zheng Y*, Chen H* (corresponding authors). An Integrated Approach for the Identification of HNF4α-Centered Transcriptional Regulatory Networks During Early Liver Regeneration. Cell Physiol Biochem. 2015;36(6):2317-2326.
  3. Chen H, Xu J, Zhou Y, Gao Y, Wang G, Xia J, Huen M, Siok W, Jiang Y, Tan L, Sun Y: Association study of stuttering candidate genes GNPTAB, GNPTG and NAGPA with dyslexia in Chinese population. BMC genetic, 2015; 16:7.
  4. Chen H, Wang G, Xia J, Zhou Y, Gao Y, Xu J, Huen MS, Siok WT, Jiang Y, Tan LH, Sun Y: Stuttering candidate genes DRD2 but not SLC6A3 is associated with developmental dyslexia in Chinese population. Behav Brain Funct, 2014; 10:29.
  5. Chen H, Lu S, Zhou J, Bai Z, Fu H, Xu X, et al. Integrated Approach for the Identification of USF1-centered Transcriptional Regulatory Networks during Liver Regeneration. BBA - Gene Regulatory Mechanisms, 2014, 1839: 415-423.
  6. Chen H, Sun Y, Dong R, Yang S, Pan C, Xiang D, et al. Mir-34a is upregulated during liver regeneration in rats and is associated with the suppression of hepatocyte proliferation. PLoS One, 2011, 6(5): e20238.
  7. Chen H, Yang S, Yang Z, Ma L, Jiang D, Mao J, et al. Inhibition of GSK-3beta decreases NF-kappaB-dependent gene expression and impairs the rat liver regeneration. J Cell Biochem, 2007, 102(5): 1281-1289.
  8. Zheng Y, Chen H (co-first), Yin M, Ye X, Chen G, Zhou X, Yin L, Zhang C, Ding B: MiR-376a and Histone Deacetylation 9 Form A Regulatory Circuitry in Hepatocellular Carcinoma. Cell Physiol Biochem, 2015; 35:729-739.
  9. Fu H, Xu H, Chen H (co-first), Li Y, Li W, Zhu Q, et al. Inhibition of Glycogen Synthase Kinase 3 Ameliorates Liver Ischemia/Reperfusion Injury via an Energy-dependent Mitochondrial Mechanis. J Hepatol, 2014, 61:816-824.
  10. Fu H, Chen H (co-first), Wang C, Xu H, Liu F, Guo M, et al. Flurbiprofen, a cyclooxygenases Inhibitor, protects mice from hepatic ischemia/reperfusion injury by inhibiting GSK-3beta signaling and mitochondrial permeability transition. Mol Med, 2012, 18:1128-1135.
  11. Pan C, Chen H (co-first), Wang L, Yang S, Fu H, Zheng Y, et al. Down-regulation of MiR-127 facilitates hepatocyte proliferation during rat liver regeneration. PLoS One, 2012, 7(6): e39151.
  12. Zhao Y, Chen H (co-first), Shang Z, Jiao B, Yuan B, Sun W, et al. SD118-Xanthocillin X (1), a Novel Marine Agent Extracted from Penicillium commune, Induces Autophagy through the Inhibition of the MEK/ERK Pathway. Mar Drugs, 2012, 10(6): 1345-1359.