张健

研究员

张健，深圳市神经科学研究院研究员，深圳大学医学部教授、神经内科主任医师。2004年获得华中科技大学同济医学院神经内科学博士。长期从事神经病学临床诊疗、教学及科研工作。在脑卒中、偏头痛、失眠、焦虑抑郁以及老年痴呆等方面积累了丰富的临床经验与研究基础。采用免疫组化和电生理学技术，在脑缺血、癫痫、焦虑抑郁、亨廷顿病、神经肌肉疾病、疼痛信号传导与调制等的细胞与分子机制及诊疗方面开展了系统、深入的研究。在国内外权威杂志发表论文多篇。

代表性论文：

  1. Mu, S., Wang, J., Zhou, G., Peng, W., He, Z., Zhao, Z., Mo, C., Qu, J., & Zhang, J.*. (2014). Transplantation of Induced Pluripotent Stem Cells Improves Functional Recovery in Huntington's Disease Rat Model. PLoS One, 9(7), e101185.
  2. Mu, S., Lin, E., Liu, B., Ma, Y., OuYang, L., Li, Y., Chen, S., Zhang, J.*, & Lei W. (2014). Melatonin reduces projection neuronal injury induced by 3-nitropropionic acid in the rat striatum. Neurodegenerative Diseases, 14(3), 139-150.
  3. Zhang, D., Gu, R., Broster, L., Jiang, Y., Luo, W., Zhang, J., & Luo, Y.J. (2014). Linking brain electrical signals elicited by current outcomes with future risk decision-making. Frontiers in Behavioral Neuroscience, 8.
  4. Li, C. Y., Lau, D. T. W., Dong, T. T. X., Zhang, J., Choi, R. C. Y., Wu, H. Q., ... & Yu, T. (2013). Dual-index evaluation of character changes in Panax ginseng CA Mey stored in different conditions. Journal of Agricultural and Food Chemistry, 61(26), 6568-6573.
  5. Song, X., Li, C. Y., Zeng, Y., Wu, H. Q., Huang, Z., Zhang, J., ... & Su, W. W. (2012). Immunomodulatory effects of crude phenylethanoid glycosides from Ligustrum purpurascens. Journal of Ethnopharmacology, 144(3), 584-591.
  6. Li, X. Y., Zhang, J.* (co-first author), Dai, J. P., Liu, X. M., & Li, Z. W. (2010). Actions of bis (7)-tacrine and tacrine on transient potassium current in rat DRG neurons and potassium current mediated by K V 4.2 expressed in Xenopus oocyte. Brain Research, 1318, 23-32.
  7. Li, Z. W., Zhang, J.* (co-first author), Ouyang, C. H., Li, C. Y., Zhao, F. B., Liu, Y. W., ... & Hu, W. P. (2009). Potentiation by WIN 55,212‐2 of GABA‐activated currents in rat trigeminal ganglion neurones. British Journal of Pharmacology, 158(8), 1904-1910.
  8. Zhang, J., Li, M., & Li, X.Y. et al. (2008). Modulation of proton-gated current by substance P in trigeminal ganglion neurons of rat. Chinese Journal of Neuromedicine, 7(6), 562-566.
  9. Zhang, J., Liao, Z.M., & Li, Z.W. et al. (2008). The outward current of S-type and O-type proton-gated ion channels in rat DRG neurons. Chinese Journal of Neuromedicine, 7(2), 134-138.
  10. Zhang J., Liao, Z.M., & Li, Z.W. et al. (2008). Current classification of proton-gated ion channels and correlation with their underlying ASICs subunit assembly in rat DRG neurons. Chinese Journal of Neuromedicine, 7(1), 6-11.
  11. Zhang, J., Luo, J.L., & Zhou, K.C. et al. (2007). Synergic effect of ATP and bradykinin on the induction of nociceptive responses: an electrophysiological and behavioural study. Chinese Journal of Neuromedicine, 6(9), 914-919.
  12. Zhang, J., Hu, W.P., & Zou, K.C. et al. (2006). Interaction of 5-HT2 and 5-HT3 receptor subtype in 5-HT-induced nociceptive responses in peripheral primary sensory nerve ending.